Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9861625 | 0.61 | ERBB2 (0.36) | KDM4EMEN1LMNATP53MAPT | |
| SCHEMBL9861392 | 0.58 | CES2 (0.39) | POLBMAPT | |
| P-Xyloquinone SCHEMBL49964 | 0.57 | PLK1 (0.60) | KDM4EMEN1LMNATP53POLB | |
| SCHEMBL3625277 | 0.53 | — | — | |
| SCHEMBL8072443 | 0.52 | — | — | |
| SCHEMBL3624714 | 0.51 | ALDH1A1 (0.50) | KDM4EMEN1LMNATP53POLB | |
| SCHEMBL7946964 | 0.51 | PLK1 (0.46) | KDM4EMEN1LMNATP53POLB | |
| SCHEMBL16488150 | 0.50 | RECQL (0.30) | POLBRECQLTDP1L3MBTL1 | |
| SCHEMBL14507718 | 0.49 | PLK1 (0.50) | KDM4EMEN1LMNATP53POLB | |
| SCHEMBL19181188 | 0.48 | CYP3A4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008425-A | Trifluoromethylation of carbonyl compounds | ETHYL CORPORATION (US) | 1991-04-16 | — | — | US | disclosed |
| US-4871877-A | Gem-disubstituted cyclohexadienones and their production | ETHYL CORPORATION (US) | 1989-10-03 | — | — | US | disclosed |