⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32679727 | 0.80 | LMNA (0.39) | — | |
| SCHEMBL10722443 | 0.68 | ALDH1A1 (0.42) | — | |
| SCHEMBL8465466 | 0.68 | — | — | |
| SCHEMBL10863391 | 0.68 | GAA (0.32) | — | |
| SCHEMBL8057256 | 0.64 | ALDH1A1 (0.61) | — | |
| SCHEMBL2844727 | 0.61 | HDAC8 (0.32) | — | |
| SCHEMBL3262195 | 0.61 | PDE4A (0.41) | — | |
| SCHEMBL10573107 | 0.58 | HSP90AA1 (0.33) | — | |
| SCHEMBL5459662 | 0.57 | LMNA (0.35) | — | |
| SCHEMBL275457 | 0.57 | LMNA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981964-A | PHOTOSTABILIZERS | ICI AMERICAS INC. (US) | 1991-01-01 | — | — | US | disclosed |
| EP-0373892-A1 | Tetramethyl piperidyl terminated triazine oligomeric esters and amides | ICI AMERICAS INC. (US) | 1990-06-20 | — | — | EP | disclosed |
| EP-0373839-A1 | Oligomeric polyesters and polyamides containing dipiperidyl triazine groups | ICI AMERICAS INC. (US) | 1990-06-20 | — | — | EP | disclosed |
| US-4889882-A | RADIATION RESISTANCE, PHOTOSTABILITY POLYMER ADDITIVE | ICI AMERICAS INC. (US) | 1989-12-26 | — | — | US | disclosed |