Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333936 | 0.86 | ALDH1A1 (0.47) | ALDH1A1GAAKMT2AKDM4EHTT | |
| SCHEMBL9333973 | 0.82 | ALDH1A1 (0.43) | ALDH1A1GAAKMT2AKDM4EHTT | |
| SCHEMBL8041736 | 0.80 | GAA (0.74) | ALDH1A1GAAKMT2AKDM4EHTT | |
| Prometon SCHEMBL9711318 | 0.76 | TP53 (0.43) | ALDH1A1GAAKMT2AKDM4EHTT | |
| SCHEMBL11689352 | 0.76 | ALDH1A1 (1.00) | ALDH1A1GAAKMT2AKDM4EHTT | |
| SCHEMBL32679727 | 0.74 | LMNA (0.39) | GAALMNACREBBPCYP1A2 | |
| SCHEMBL10721622 | 0.74 | LMNA (0.48) | ALDH1A1GAAKMT2AKDM4ELMNA | |
| SCHEMBL29710208 | 0.71 | HTT (1.00) | ALDH1A1GAAKMT2AKDM4EHTT | |
| SCHEMBL20117984 | 0.70 | GAA (0.61) | ALDH1A1GAAKMT2AKDM4EHTT | |
| SCHEMBL9970686 | 0.70 | GAA (0.61) | ALDH1A1GAAKMT2AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130332-A | USING A GROUP 8 METAL CATALYST AND ALDEHYDES OR KETONE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-10-10 | — | — | US | disclosed |
| EP-0760369-A1 | PROCESS FOR ALKYLATING TRIAZINE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-03-05 | — | — | EP | disclosed |