Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23017583 | 0.85 | HTT (0.39) | ALDH1A1MAPTNOS3NOS1NOS2 | |
| SCHEMBL28181649 | 0.76 | KCNH2 (0.35) | KCNH2SCN5ASMN1; SMN2 | |
| SCHEMBL9861529 | 0.75 | SHBG (0.34) | KCNH2SCN5ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL728561 | 0.75 | ALDH1A1 (0.34) | SCN5AALDH1A1 | |
| SCHEMBL9861942 | 0.73 | KCNH2 (0.33) | KCNH2SCN5ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL15169933 | 0.73 | HPGD (0.42) | LMNAHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL725861 | 0.72 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL10344853 | 0.72 | SELL (0.44) | HPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL20811095 | 0.71 | — | — | |
| SCHEMBL31603744 | 0.70 | KCNH2 (0.32) | KCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041668-A | Polyurethane Chain Extenders, Hardeners for Epoxy Resins | ETHYL CORPORATION (US) | 1991-08-20 | — | — | US | claimed |
| US-5041668-A | Polyurethane Chain Extenders, Hardeners for Epoxy Resins | ETHYL CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |