Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 6/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | AOC1 | P19801 | 2/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725861 | 0.83 | ALDH1A1 (0.49) | ALDH1A1ELANECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2968661 | 0.83 | ELANE (0.33) | ELANETRPM8ALOX15ALOX12SCN5A | |
| SCHEMBL727390 | 0.77 | ELANE (0.35) | ELANEALOX15ALOX12SCN5AAOC1 | |
| SCHEMBL726976 | 0.76 | LMNA (0.30) | ELANE | |
| SCHEMBL9861627 | 0.75 | KCNH2 (0.33) | ALDH1A1SCN5A | |
| SCHEMBL2971453 | 0.74 | EED (0.33) | ALDH1A1AOC1AOC3 | |
| SCHEMBL10037111 | 0.71 | ELANE (0.45) | ALDH1A1ELANECYP2C19ALOX15SCN5A | |
| SCHEMBL2970801 | 0.71 | TSHR (0.35) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11288221 | 0.69 | PTGS2 (0.46) | ALDH1A1ELANEALOX15ALOX12KDM4E | |
| SCHEMBL4493246 | 0.67 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4797063-B2 | — | — | 2011-10-19 | — | — | JP | claimed |
| US-20080315155-A1 | Diamines Having Reduced Color | ALBEMARLE CORPORATION (US) | 2008-12-25 | — | — | US | claimed |
| JP-2008534585-A | — | — | 2008-08-28 | — | — | JP | claimed |
| US-20080004406-A1 | DIIMINES AND SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2008-01-03 | — | — | US | claimed |
| EP-1868987-A1 | DIIMINES AND SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2007-12-26 | — | — | EP | claimed |
| WO-2006104528-A1 | DIIMINES AND SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2006-10-05 | — | — | WO | claimed |
| US-20060217567-A1 | Diimines and secondary diamines | ALBEMARLE CORPORATION | 2006-09-28 | — | — | US | claimed |
| US-8212078-B2 | Making chain extenders with slower cure rates; reacting a ketone and/or aldehyde with a primary amine in the presence of an acidic ion exchange resin and hydrogenation agent; making diimine same way but excluding hydrogenation agent; e.g. N,N'-di-5-nonyl-isophoronediamine | ALBEMARLE CORPORATION (US) | 2012-07-03 | — | — | US | disclosed |
| US-7767858-B2 | Diimines and secondary diamines | ALBEMARLE CORPORATION (US) | 2010-08-03 | — | — | US | disclosed |
| EP-2143707-A2 | Secondary diamine | Albermarle Corporation (US) | 2010-01-13 | — | — | EP | disclosed |
| US-20080315155-A1 | Diamines Having Reduced Color | ALBEMARLE CORPORATION (US) | 2008-12-25 | — | — | US | disclosed |
| US-20080262187-A1 | Blends of Diamines Having Reduced Color | ALBEMARLE CORPORATION (US) | 2008-10-23 | — | — | US | disclosed |
| EP-1966265-A2 | BLENDS OF DIAMINES HAVING REDUCED COLOR | Albermarle Corporation (US) | 2008-09-10 | — | — | EP | disclosed |
| EP-1868987-A1 | DIIMINES AND SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2007-12-26 | — | — | EP | disclosed |
| US-7288677-B2 | Diimines and secondary diamines | ALBEMARLE CORPORATION (US) | 2007-10-30 | — | — | US | disclosed |
| WO-2007079365-A2 | BLENDS OF DIAMINES HAVING REDUCED COLOR | ALBEMARLE CORPORATION (US) | 2007-07-12 | — | — | WO | disclosed |
| WO-2007079367-A1 | DIAMINES HAVING REDUCED COLOR | ALBEMARLE CORPORATION (US) | 2007-07-12 | — | — | WO | disclosed |
| WO-2006104528-A1 | DIIMINES AND SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2006-10-05 | — | — | WO | disclosed |
| US-20060217567-A1 | Diimines and secondary diamines | ALBEMARLE CORPORATION | 2006-09-28 | — | — | US | disclosed |
| US-3943158-A | POLYURETHANE MONOMERS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004406-A1 | DIIMINES AND SECONDARY DIAMINES | DDT, DDC, AOC1 | ALDH1A1 412/4885ELANE 3408/4885CYP1A2 258/4885 |
| US-20080262187-A1 | Blends of Diamines Having Reduced Color | DDT, DDC, AOC1 | ALDH1A1 181/4885ELANE 3801/4885CYP1A2 524/4885 |
| US-20080315155-A1 | Diamines Having Reduced Color | DDT, DPYD, DDC | ALDH1A1 213/4885ELANE 3624/4885CYP1A2 821/4885 |
| US-20060217567-A1 | Diimines and secondary diamines | DDT, DDC, AOC1 | ALDH1A1 412/4885ELANE 3408/4885CYP1A2 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.