Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14509458 | 0.89 | SHBG (0.33) | SHBGDHFRBACE1HSPA5KMT2A | |
| SCHEMBL5509475 | 0.81 | SHBG (0.32) | SHBGDHFRLMNAHPGD | |
| SCHEMBL727390 | 0.78 | ELANE (0.35) | SHBGDHFRSCN5AGAA | |
| SCHEMBL9861627 | 0.75 | KCNH2 (0.33) | KCNH2SCN5ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL727589 | 0.74 | ALDH1A1 (0.44) | GAASMN1; SMN2 | |
| SCHEMBL13866793 | 0.73 | CA5A (0.42) | SCN5AKMT2AMEN1HPGDHTT | |
| SCHEMBL12284735 | 0.73 | GAA (0.50) | SCN5AKMT2AMEN1GAALMNA | |
| SCHEMBL25314219 | 0.72 | HTT (0.42) | HSPA5GAALMNAHPGDHTT | |
| SCHEMBL4364941 | 0.72 | DHFR (0.53) | SHBGDHFRBACE1HSPA5KMT2A | |
| SCHEMBL48459 | 0.72 | HTT (0.50) | SHBGDHFRBACE1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041668-A | Polyurethane Chain Extenders, Hardeners for Epoxy Resins | ETHYL CORPORATION (US) | 1991-08-20 | — | — | US | claimed |
| US-5041668-A | Polyurethane Chain Extenders, Hardeners for Epoxy Resins | ETHYL CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |