SCHEMBL2220231

SCHEMBL2220231

Cc1c(O)cc(O)c(O)c1C(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 2/20 0.50
BCL2L1 Q07817 2/20 0.50
MCL1 Q07820 2/20 0.50
BCL2L2 Q92843 1/20 0.50
GABRA1 P14867 4/20 0.40
GABRB2 P47870 2/20 0.40
SELL P14151 1/20 0.40
SELP P16109 1/20 0.40
SELE P16581 1/20 0.40
ACHE P22303 1/20 0.40
BID P55957 1/20 0.36
BCL2A1 Q16548 1/20 0.36
LDHA P00338 2/20 0.36
LDHB P07195 2/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
TRPA1 O75762 2/20 0.35
LMNA P02545 2/20 0.35
FFAR1 O14842 1/20 0.35
PTGS1 P23219 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15833918 0.82 CA1 (0.48) BCL2BCL2L1MCL1BCL2L2GABRA1
SCHEMBL9861633 0.81 BCL2 (0.46) BCL2BCL2L1MCL1BCL2L2GABRA1
SCHEMBL14958609 0.74 MCL1 (0.87) BCL2BCL2L1MCL1BCL2L2BID
SCHEMBL9008227 0.74 AHR (0.43) BCL2BCL2L1MCL1BCL2L2GABRA1
SCHEMBL12572590 0.73 ACHE (0.37) BCL2BCL2L1MCL1BCL2L2ACHE
SCHEMBL19768987 0.73 BCL2 (0.39) BCL2BCL2L1MCL1BCL2L2GABRA1
SCHEMBL15014303 0.73 GABRA1 (0.47) BCL2BCL2L1MCL1BCL2L2GABRA1
SCHEMBL5382137 0.71 LMNA (0.42) BCL2BCL2L1MCL1BCL2L2GABRA1
SCHEMBL9862023 0.71 BCL2 (0.50) BCL2BCL2L1MCL1BCL2L2GABRA1
SCHEMBL20528331 0.71 ALDH1A1 (0.39) BCL2BCL2L1MCL1BCL2L2GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9298113-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2016-03-29 US disclosed
US-9122183-B2 Electrophotographic photoreceptor, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2015-09-01 US disclosed
US-9081353-B2 Cleaner, and process cartridge and image forming apparatus using the cleaner RICOH COMPANY, LTD. (JP) 2015-07-14 US disclosed
US-20140193172-A1 CLEANER, AND PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS USING THE CLEANER RICOH COMPANY, LTD. (JP) 2014-07-10 US disclosed
US-20130244150-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-09-19 US disclosed
US-20110173807-A1 DISPERSION FOR DISPOSING FINE PARTICLE AT PREDETERMINED POINT ON SUBSTRATE BY INK-JET PRINTING NATOCO CO., LTD. (JP) 2011-07-21 US disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed
EP-0032062-B2 HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-16 EP disclosed
EP-0032062-B1 HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-04-03 EP disclosed
US-4345054-A High-molecular-weight novolak types substituted phenolic resins and process for preparation thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-08-17 US disclosed
EP-0032062-A2 High-molecular-weight novolak substituted phenolic resins and their preparation MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1981-07-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM BCL2 4712/4885BCL2L1 4472/4885MCL1 4051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.