SCHEMBL10813630

SCHEMBL10813630

CCCCN(c1nc(NCCCO)nc(N(CC)CC)n1)C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 3/20 0.35
KMT2A Q03164 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9091672 0.95 SLC29A1 (0.35) SLC29A1KMT2A
SCHEMBL9861690 0.93 KMT2A (0.37) SLC29A1KMT2A
SCHEMBL10910189 0.91 KMT2A (0.38) SLC29A1KMT2A
SCHEMBL226334 0.89 SLC29A1 (0.35) SLC29A1
SCHEMBL9091458 0.89 SLC29A1 (0.39) SLC29A1KMT2A
SCHEMBL10801042 0.89 SMN1; SMN2 (0.33) SLC29A1
SCHEMBL3136072 0.88 SLC29A1 (0.33) SLC29A1
SCHEMBL10167577 0.87 NPY1R (0.33) SLC29A1KMT2A
SCHEMBL11101385 0.87 KMT2A (0.40) SLC29A1KMT2A
SCHEMBL9367814 0.87 DNM2 (0.34) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0061659-B1 PIPERIDINE GROUPS CONTAINING ESTERS,METHODS FOR THEIR PREPARATION, THEIR USE AS STABILISING AGENTS FOR POLYMERS, AND POLYMERS CONTAINING THESE COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-22 EP disclosed
EP-0064752-B1 PHOSPHAZENES SUBSTITUTED BY PIPERIDYL GROUPS, PROCESS FOR PREPARING THEM, THEIR USE AS STABILIZERS AND POLYMER COMPOSITIONS STABILIZED BY THEM HOECHST AKTIENGESELLSCHAFT (DE) 1986-01-08 EP disclosed
US-4476302-A PHOTOSTABILITY HOECHST AKTIENGESELLSCHAFT (DE) 1984-10-09 US disclosed
US-4451400-A Phosphazenes useful as stabilizers in polymers HOECHST AKTIENGESELLSCHAFT (DE) 1984-05-29 US disclosed
EP-0064752-A2 Phosphazenes substituted by piperidyl groups, process for preparing them, their use as stabilizers and polymer compositions stabilized by them HOECHST AKTIENGESELLSCHAFT (DE) 1982-11-17 EP disclosed
EP-0061659-A1 Piperidine groups containing esters,methods for their preparation, their use as stabilising agents for polymers, and polymers containing these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1982-10-06 EP disclosed