SCHEMBL9862047

SCHEMBL9862047

c1ccc2c(c1)COPO2

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.39
MAOB P27338 2/20 0.39
NISCH Q9Y2I1 2/20 0.35
ABCG2 Q9UNQ0 1/20 0.33
ITGB2 P05107 1/20 0.33
ICAM1 P05362 1/20 0.33
ITGAL P20701 1/20 0.33
OXTR P30559 1/20 0.33
LMNA P02545 3/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
KMT2A Q03164 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
GAA P10253 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CRHBP P24387 2/20 0.30
CRHR2 Q13324 2/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9567365 0.84 MAOB (0.39) MAOAMAOBLMNASMN1; SMN2KMT2A
SCHEMBL295869 0.78 MAOA (0.37) MAOAMAOBOXTRLMNASMN1; SMN2
SCHEMBL3889563 0.76 MAOA (0.61) MAOAMAOBABCG2ITGB2ICAM1
SCHEMBL29538767 0.76 MAOA (0.61) MAOAMAOBABCG2ITGB2ICAM1
SCHEMBL30349594 0.69
SCHEMBL346944 0.69
SCHEMBL10170816 0.69 OXTR (0.52) MAOAMAOBNISCHABCG2ITGB2
SCHEMBL30058027 0.68 ABCG2 (0.40) MAOAMAOBABCG2ITGB2ICAM1
SCHEMBL2583969 0.68
Bromide SCHEMBL22498666 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0256407-B1 INSECTICIDAL AGENT NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1991-03-06 EP claimed
EP-0106169-A1 Substituted 2-(2,6-di-t-butyl-4-alkylphenoxy) 4H-1,3,2-benzodioxaphosphorins and compositions thereof The B.F. GOODRICH Company (US) 1984-04-25 EP claimed
US-12202850-B2 Cyclobutyl purine derivative or salt thereof FUJIFILM CORPORATION (JP) 2025-01-21 US disclosed
CN-117897427-A Stabilizer combinations for preventing degradation of synthetic polymers 巴斯夫欧洲公司 2024-04-16 CN disclosed
EP-3831388-B1 CYCLOPENTENYL PURINE DERIVATIVE OR SALT THEREOF FOR USE IN SUPPRESSING ADENOVIRUS FUJIFILM CORP (JP) 2024-02-28 EP disclosed
US-20230295202-A1 CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF FUJIFILM CORPORATION (JP) 2023-09-21 US disclosed
EP-3831836-B1 CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF FUJIFILM CORP (JP) 2023-09-06 EP disclosed
EP-3831388-A1 CYCLOPENTENYL PURINE DERIVATIVE OR SALT THEREOF FUJIFILM Corporation (JP) 2021-06-09 EP disclosed
EP-3831836-A1 CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF FUJIFILM Corporation (JP) 2021-06-09 EP disclosed
US-20210155644-A1 CYCLOPENTENYL PURINE DERIVATIVE OR SALT THEREOF FUJIFILM CORPORATION (JP) 2021-05-27 US disclosed
US-20210147456-A1 CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF FUJIFILM CORPORATION (JP) 2021-05-20 US disclosed
CN-112512529-A Cyclopentene purine derivatives or salts thereof 富士胶片株式会社 2021-03-16 CN disclosed
EP-3214090-B1 THIONUCLEOSIDE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FUJIFILM CORP (JP) 2020-08-19 EP disclosed
US-10385089-B2 Thionucleoside derivative or salt thereof, and pharmaceutical composition FUJIFILM CORPORATION (JP) 2019-08-20 US disclosed
US-20180319834-A1 THIONUCLEOSIDE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FUJIFILM CORPORATION (JP) 2018-11-08 US disclosed
US-10059734-B2 Thionucleoside derivative or salt thereof, and pharmaceutical composition FUJIFILM CORPORATION (JP) 2018-08-28 US disclosed
EP-3214090-A1 THIONUCLEOSIDE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION Fujifilm Corporation (JP) 2017-09-06 EP disclosed
US-20170233429-A1 THIONUCLEOSIDE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION FUJIFILM CORPORATION (JP) 2017-08-17 US disclosed
EP-0054431-B1 OPTICAL ISOMER OF A TRIAZOLYLPENTENOL, AND ITS PRODUCTION AND USE AS FUNGICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-03-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295202-A1 CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF SLC28A1, SLC20A1, SLC29A1 MAOA 3616/4885MAOB 2102/4885NISCH 4691/4885
US-20210147456-A1 CYCLOBUTYL PURINE DERIVATIVE OR SALT THEREOF SLC28A1, SLC20A1, SLC29A1 MAOA 3616/4885MAOB 2102/4885NISCH 4691/4885
US-20180319834-A1 THIONUCLEOSIDE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION SLC11A2, RNASE1, KRAS MAOA 4882/4885MAOB 4856/4885NISCH 4055/4885
US-12202850-B2 Cyclobutyl purine derivative or salt thereof SLC28A1, SLC20A1, SLC29A1 MAOA 3616/4885MAOB 2102/4885NISCH 4691/4885
US-10385089-B2 Thionucleoside derivative or salt thereof, and pharmaceutical composition SLC11A2, RNASE1, KRAS MAOA 4882/4885MAOB 4856/4885NISCH 4055/4885
US-10059734-B2 Thionucleoside derivative or salt thereof, and pharmaceutical composition SLC11A2, RNASE1, TYMP MAOA 4884/4885MAOB 4862/4885NISCH 4145/4885
US-20210155644-A1 CYCLOPENTENYL PURINE DERIVATIVE OR SALT THEREOF SLC28A1, SLC20A1, NOX1 MAOA 2832/4885MAOB 2304/4885NISCH 4556/4885
US-20170233429-A1 THIONUCLEOSIDE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION SLC11A2, RNASE1, TYMP MAOA 4884/4885MAOB 4862/4885NISCH 4145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.