SCHEMBL9862337

SCHEMBL9862337

CC1(C)C2CCC1(CO)CC2

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.32
LMNA P02545 2/20 0.31
MAPT P10636 2/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
RECQL P46063 1/20 0.31
APOBEC3A P31941 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11615961 0.81 L3MBTL1 (0.31) L3MBTL1
SCHEMBL14407611 0.75 LMNA (0.31) LMNAMAPTMEN1ALDH1A1KMT2A
SCHEMBL5983720 0.75 LMNA (0.31) LMNAMAPTMEN1ALDH1A1KMT2A
SCHEMBL19338320 0.73 LMNA (0.30) LMNAMAPTMEN1ALDH1A1KMT2A
SCHEMBL11613171 0.73 EPHX2 (0.32) L3MBTL1LMNAMAPTMEN1ALDH1A1
SCHEMBL3456522 0.72 CXCR3 (0.37) LMNAMAPTMEN1ALDH1A1KMT2A
SCHEMBL11612913 0.71
SCHEMBL9862195 0.70 MEN1 (0.32) LMNAMAPTMEN1ALDH1A1KMT2A
SCHEMBL11611278 0.69 KDM4E (0.30)
SCHEMBL12888600 0.69 CXCR3 (0.38) LMNAMAPTMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240317706-A1 COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF MONTE ROSA THERAPEUTICS AG (CH) 2024-09-26 US disclosed
WO-2023069720-A1 COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF MONTE ROSA THERAPEUTICS, INC. (US) 2023-04-27 WO disclosed
WO-1991002711-A2 7,7-DIMETHYLNORBORNANE DERIVATIVES THE COCA-COLA COMPANY (US) 1991-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240317706-A1 COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF CDK2, SKP2, CDK1 L3MBTL1 1254/4885LMNA 2140/4885MAPT 3248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.