Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28866226 | 0.83 | ALDH1A1 (0.42) | ALDH1A1ALOX15MAPK1CYP2C19HIF1A | |
| SCHEMBL1357103 | 0.83 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAPK1CYP2C19HIF1A | |
| SCHEMBL1356738 | 0.81 | ALDH1A1 (0.43) | ALDH1A1ALOX15MAPK1CYP2C19HIF1A | |
| SCHEMBL603883 | 0.79 | CYP1A2 (0.45) | ALDH1A1ALOX15MAPK1CYP2C19HIF1A | |
| SCHEMBL10917315 | 0.77 | CYP2C19 (0.41) | ALDH1A1ALOX15MAPK1CYP2C19HIF1A | |
| SCHEMBL5879105 | 0.77 | MAPK1 (0.56) | ALDH1A1ALOX15MAPK1CYP2C19HIF1A | |
| SCHEMBL4426984 | 0.77 | ALDH1A1 (0.52) | ALDH1A1ALOX15MAPK1CYP2C19HIF1A | |
| SCHEMBL7759605 | 0.76 | LTA4H (0.43) | ALDH1A1ALOX15MAPK1CYP2C19KDM4E | |
| SCHEMBL14946776 | 0.75 | ALDH1A1 (0.42) | ALDH1A1ALOX15MAPK1CYP2C19HIF1A | |
| SCHEMBL6241174 | 0.75 | KIF11 (0.56) | ALDH1A1ALOX15MAPK1CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990331-A | Synthetic hormones | APIS INDUSTRIES LTD. (CA) | 1991-02-05 | — | — | US | disclosed |