Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 5/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862582 | 0.89 | MTNR1A (0.47) | MTNR1ACNR2CNR1 | |
| SCHEMBL9862642 | 0.80 | CNR2 (0.51) | CNR2CNR1 | |
| SCHEMBL9418189 | 0.72 | TRPV1 (0.50) | HPGD | |
| SCHEMBL5335468 | 0.71 | MTNR1A (0.52) | MTNR1ACNR2CNR1 | |
| SCHEMBL5341536 | 0.70 | MTNR1A (0.51) | MTNR1A | |
| SCHEMBL5344418 | 0.70 | MTNR1A (0.51) | MTNR1A | |
| SCHEMBL5342713 | 0.70 | MTNR1A (0.51) | MTNR1A | |
| SCHEMBL5335473 | 0.69 | MTNR1A (0.52) | MTNR1ACNR2CNR1 | |
| SCHEMBL5342717 | 0.69 | MTNR1A (0.51) | MTNR1ACNR1 | |
| SCHEMBL5344422 | 0.69 | MTNR1A (0.51) | MTNR1ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021414-A | Antiestrogen | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-04 | — | — | US | disclosed |
| US-4904661-A | ANTIESTROGENS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-27 | — | — | US | disclosed |
| US-4732912-A | ANTIESTROGENS, ANTITUMOR AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-22 | — | — | US | disclosed |
| EP-0124369-A1 | Phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-07 | — | — | EP | disclosed |