Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 6/20 | 0.45 |
| ▸ | CNR1 | P21554 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862542 | 0.89 | MTNR1A (0.44) | MTNR1ACNR2CNR1 | |
| SCHEMBL9862642 | 0.84 | CNR2 (0.51) | TRPV1CNR2CNR1 | |
| SCHEMBL5335468 | 0.70 | MTNR1A (0.52) | MTNR1ATRPV1CNR2CNR1 | |
| SCHEMBL5341536 | 0.70 | MTNR1A (0.51) | MTNR1ATRPV1ALDH1A1 | |
| SCHEMBL5342713 | 0.70 | MTNR1A (0.51) | MTNR1ATRPV1 | |
| SCHEMBL14010836 | 0.70 | L3MBTL1 (0.56) | — | |
| SCHEMBL14010834 | 0.70 | L3MBTL1 (0.56) | — | |
| SCHEMBL9418189 | 0.69 | TRPV1 (0.50) | TRPV1 | |
| SCHEMBL3815984 | 0.69 | MTNR1A (0.75) | MTNR1ATRPV1ALDH1A1 | |
| SCHEMBL13422245 | 0.68 | THRB (0.55) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021414-A | Antiestrogen | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-04 | — | — | US | disclosed |
| US-4904661-A | ANTIESTROGENS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-27 | — | — | US | disclosed |
| US-4732912-A | ANTIESTROGENS, ANTITUMOR AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-22 | — | — | US | disclosed |
| EP-0124369-A1 | Phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-11-07 | — | — | EP | disclosed |