Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25984798 | 0.88 | NR3C2 (0.53) | NR3C2HPGDKMT2AHSD11B1HSP90AA1 | |
| SCHEMBL25349070 | 0.81 | TP53 (0.61) | HPGDKMT2AHSD11B1HSP90AA1ALDH1A1 | |
| SCHEMBL11690284 | 0.80 | HSD11B1 (0.40) | NR3C2HPGDKMT2AHSD11B1HSP90AA1 | |
| SCHEMBL11770408 | 0.77 | KMT2A (0.64) | KMT2AALDH1A1KDM4ERAB9AHTT | |
| SCHEMBL6678148 | 0.77 | NPSR1 (0.50) | NR3C2HPGDKMT2AALDH1A1KDM4E | |
| SCHEMBL28075002 | 0.75 | L3MBTL1 (0.44) | NR3C2HPGDKMT2AHSD11B1ALDH1A1 | |
| SCHEMBL11416543 | 0.75 | RAB9A (0.41) | HPGDKMT2AALDH1A1KDM4EMLYCD | |
| SCHEMBL27338414 | 0.75 | KMT2A (0.44) | HPGDKMT2AHSD11B1KDM4EL3MBTL1 | |
| SCHEMBL11409191 | 0.73 | MLYCD (0.43) | HPGDKMT2AALDH1A1KDM4EMLYCD | |
| SCHEMBL11410535 | 0.73 | HPGD (0.60) | HPGDKMT2AALDH1A1MLYCDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032592-A | Antiandrogens | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-07-16 | — | — | US | disclosed |