Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201754 | 0.81 | PPARA (0.53) | LMNAHTTMAPTALOX12PPARA | |
| SCHEMBL17653510 | 0.79 | PPARG (0.42) | L3MBTL1MAPTRECQLNPSR1PPARA | |
| SCHEMBL4752621 | 0.79 | PPARG (0.42) | L3MBTL1MAPTRECQLNPSR1PPARA | |
| SCHEMBL8075911 | 0.73 | ALDH1A1 (0.38) | L3MBTL1MAPTRECQLNPSR1PPARA | |
| SCHEMBL28230446 | 0.73 | PIN1 (0.49) | HTTMAPTRECQLNPSR1PPARA | |
| SCHEMBL6188978 | 0.71 | LMNA (0.55) | L3MBTL1LMNAHTTALOX12RIPK1 | |
| SCHEMBL1895641 | 0.70 | TAAR1 (0.58) | — | |
| SCHEMBL20077094 | 0.69 | LMNA (0.53) | L3MBTL1LMNAHTTMAPTRIPK1 | |
| SCHEMBL6435539 | 0.69 | CNR1 (0.67) | L3MBTL1LMNAHTTRIPK1ALDH1A1 | |
| SCHEMBL27612101 | 0.69 | PRSS1 (0.35) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988828-A | Antiulcer agents, antagonist for histamine H2 receptors | FUJIREBIO KABUSHIKI KAISHA (JP) | 1991-01-29 | — | — | US | disclosed |
| EP-0318036-A2 | Phenoxypropyl derivatives | FUJIREBIO KABUSHIKI KAISHA (JP) | 1989-05-31 | — | — | EP | disclosed |