Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30810444 | 1.00 | IAPP (0.53) | IAPPADAMTS4ALDH1A1EGFRCA1 | |
| SCHEMBL9863155 | 0.92 | IAPP (0.50) | IAPP | |
| SCHEMBL9863325 | 0.92 | IAPP (0.50) | IAPP | |
| SCHEMBL10414030 | 0.89 | IAPP (0.59) | IAPPADAMTS4ALDH1A1EGFRCA1 | |
| SCHEMBL8894033 | 0.89 | GABRA1 (0.48) | IAPPALOX5PTGS2MPOSLC6A4 | |
| SCHEMBL1951548 | 0.86 | IAPP (0.57) | IAPPADAMTS4ALDH1A1EGFRCA1 | |
| SCHEMBL30046415 | 0.86 | IAPP (0.57) | IAPPADAMTS4ALDH1A1EGFRCA1 | |
| SCHEMBL9153692 | 0.82 | ALOX5 (0.47) | IAPPALOX5PTGS2 | |
| SCHEMBL169275 | 0.82 | TAAR1 (0.58) | CA2HSD17B10MPOSLC6A4HSPA5 | |
| SCHEMBL633288 | 0.81 | TAAR1 (0.52) | IAPPADAMTS4ALDH1A1EGFRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103923072-A | Substituted Indazole Derivatives Active As Kinase Inhibitors | NERVIANO MEDICAL SCIENCES SRL | 2014-07-16 | — | — | CN | disclosed |
| WO-2011022511-A2 | METHODS OF REDUCING LIGNIN AND PRODUCTS THEREOF | STRATEGIC ENZYME APPLICATIONS, INC. (US) | 2011-02-24 | — | — | WO | disclosed |
| US-7777073-B2 | Topical delivery system for antiaging and skin whitening agents | BIODERM RESEARCH (US) | 2010-08-17 | — | — | US | disclosed |
| US-20090074691-A1 | Topical Delivery System for Antiaging and Skin Whitening Agents | BIODERM RESEARCH (US) | 2009-03-19 | — | — | US | disclosed |
| EP-0669331-B1 | Benzodioxane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-10-11 | — | — | EP | disclosed |
| US-5500443-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-03-19 | — | — | US | disclosed |
| EP-0669331-A1 | Benzodioxane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090074691-A1 | Topical Delivery System for Antiaging and Skin Whitening Agents | TYR, MMP17, MMP1 | IAPP 2230/4885ADAMTS4 1319/4885ALDH1A1 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.