SCHEMBL9153692

SCHEMBL9153692

OCCCCc1cccc(CCCCO)c1O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.47
PTGS2 P35354 1/20 0.47
GABRA1 P14867 2/20 0.46
GABRB2 P47870 2/20 0.46
IAPP P10997 3/20 0.38
HMGB1 P09429 1/20 0.37
TYR P14679 1/20 0.37
BID P55957 4/20 0.37
MCL1 Q07820 4/20 0.37
BCL2L1 Q07817 3/20 0.37
BAK1 Q16611 3/20 0.37
KAT8 Q9H7Z6 2/20 0.37
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
EP300 Q09472 1/20 0.37
KAT2A Q92830 1/20 0.37
KAT2B Q92831 1/20 0.37
KAT5 Q92993 1/20 0.37
SAE1 Q9UBE0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8894033 0.93 GABRA1 (0.48) ALOX5PTGS2GABRA1GABRB2IAPP
SCHEMBL9863155 0.87 IAPP (0.50) IAPPBIDMCL1BCL2L1BAK1
SCHEMBL9863325 0.87 IAPP (0.50) IAPPBIDMCL1BCL2L1BAK1
SCHEMBL8997129 0.86 ALDH1A1 (0.48) ALOX5PTGS2GABRA1GABRB2IAPP
SCHEMBL11109102 0.82 GABRA1 (0.52) ALOX5PTGS2GABRA1GABRB2IAPP
SCHEMBL9672220 0.82 LIPG (0.43) BIDMCL1BCL2L1BAK1
SCHEMBL30750761 0.82 LIPG (0.43) BIDMCL1BCL2L1BAK1
SCHEMBL30810444 0.82 IAPP (0.53) ALOX5PTGS2IAPP
SCHEMBL1236262 0.82 IAPP (0.53) ALOX5PTGS2IAPP
SCHEMBL6567369 0.81 CA2 (0.53) ALOX5PTGS2GABRA1GABRB2IAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0369219-B1 Light-sensitive compounds, preparation of a light-sensitive mixture therewith and a recording material HOECHST AG (DE) 1995-01-04 EP disclosed
US-5114816-A RADIATION-SENSITIVE COMPOUNDS, RADIATION-SENSITIVE MIXTURE PREPARED THEREWITH AND COPYING MATERIAL HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-19 US disclosed
EP-0369219-A1 Light-sensitive compounds, preparation of a light-sensitive mixture therewith and a recording material HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-23 EP disclosed