Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 4/20 | 0.43 |
| ▸ | CES1 | P23141 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631701 | 0.71 | LMNA (0.56) | MAPTPPARAPPARDPPARGALDH1A1 | |
| SCHEMBL1405603 | 0.71 | CA1 (0.65) | MAPTACHECA1CA2PTGS2 | |
| SCHEMBL1405602 | 0.71 | CA1 (0.65) | MAPTACHECA1CA2PTGS2 | |
| SCHEMBL28593719 | 0.70 | PTGS2 (0.46) | MAPTCES2CES1ACHECA1 | |
| SCHEMBL490716 | 0.69 | LDHA (1.00) | LDHAPPARAPPARGCYP1A2 | |
| SCHEMBL28982575 | 0.69 | MAPT (0.53) | MAPTCES2CES1ACHECA1 | |
| SCHEMBL8603711 | 0.69 | MAPT (0.46) | MAPTCES2CES1ACHECA1 | |
| SCHEMBL11486390 | 0.69 | LDHA (0.55) | LDHACES2CES1CA1CA2 | |
| SCHEMBL7162814 | 0.68 | CA1 (0.58) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL9863577 | 0.68 | MAPT (0.51) | MAPTCES2CES1ACHECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988787-A | Addition copolymers from unsaturated isocyanates and acrylonitrile, maleic anhydride, maleimide or acrylic esters | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |