Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96633 | 0.64 | HSD17B10 (0.46) | MAOAMAOBLMNACYP2A6CA1 | |
| SCHEMBL194685 | 0.64 | LMNA (0.42) | MAOAMAOBLMNACYP2A6CA1 | |
| SCHEMBL28307146 | 0.64 | LMNA (0.42) | MAOAMAOBLMNACYP2A6CA1 | |
| SCHEMBL535420 | 0.64 | LMNA (0.42) | MAOAMAOBLMNACYP2A6CA1 | |
| SCHEMBL27525368 | 0.63 | HSD17B10 (0.44) | MAOAMAOBLMNACYP2A6CA1 | |
| SCHEMBL939907 | 0.63 | HSD17B10 (0.44) | MAOAMAOBLMNACYP2A6CA1 | |
| SCHEMBL3624201 | 0.61 | — | — | |
| SCHEMBL9065756 | 0.61 | LMNA (0.38) | MAOAMAOBLMNACYP2A6CA1 | |
| SCHEMBL9065752 | 0.61 | LMNA (0.38) | MAOAMAOBLMNACYP2A6CA1 | |
| SCHEMBL11444324 | 0.60 | HPGD (0.39) | MAOAMAOBLMNACYP2A6CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407955-A1 | New hetrazepines acting as PAF antagonists, process for their production and their use as drugs | BOEHRINGER INGELHEIM KG (DE) | 1991-01-16 | — | — | EP | disclosed |