Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31171944 | 1.00 | GAA (0.57) | GAAKDM4EL3MBTL1ALDH1A1TSHR | |
| SCHEMBL31228347 | 0.81 | TGM2 (0.65) | KDM4EALDH1A1SMN1; SMN2TGM2 | |
| SCHEMBL613090 | 0.81 | TGM2 (0.65) | KDM4EALDH1A1SMN1; SMN2TGM2 | |
| SCHEMBL6858019 | 0.80 | GAA (0.66) | GAAKDM4EL3MBTL1ALDH1A1TSHR | |
| SCHEMBL9659766 | 0.78 | MAOB (0.38) | GAAKDM4EL3MBTL1ALDH1A1TSHR | |
| SCHEMBL4766358 | 0.78 | GAA (0.69) | GAAKDM4EL3MBTL1ALDH1A1TSHR | |
| SCHEMBL30107521 | 0.78 | GAA (0.64) | GAAKDM4EL3MBTL1ALDH1A1TSHR | |
| SCHEMBL6222692 | 0.78 | GAA (0.64) | GAAKDM4EL3MBTL1ALDH1A1TSHR | |
| SCHEMBL21808550 | 0.78 | TGM2 (0.50) | GAAKDM4EALDH1A1TGM2HPGD | |
| SCHEMBL31596298 | 0.78 | MAPK3 (0.38) | GAAKDM4EALDH1A1TGM2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106977474-A | One kind substitution benzofurane acrylamide derivative of 2 cyano group 3 and its production and use | 四川大学 | 2017-07-25 | — | — | CN | claimed |
| CN-106977474-B | Substituted 2-cyano-3-phenyl furan-acrylamide derivative and preparation method and application thereof | 四川大学 | 2020-04-07 | — | — | CN | disclosed |
| US-20190293641-A1 | ASSAY | IMPERIAL COLLEGE INNOVATIONS, LTD. (GB) | 2019-09-26 | — | — | US | disclosed |
| WO-2018033753-A2 | ASSAY | IMPERIAL INNOVATIONS LIMITED (GB) | 2018-02-22 | — | — | WO | disclosed |
| CN-106977474-A | One kind substitution benzofurane acrylamide derivative of 2 cyano group 3 and its production and use | 四川大学 | 2017-07-25 | — | — | CN | disclosed |
| EP-0409565-A1 | Rubber composition useful for tires | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-01-23 | — | — | EP | disclosed |