Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CGAS | Q8N884 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.49 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.49 |
| ▸ | ABAT | P80404 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 10/20 | 0.47 |
| ▸ | PRKDC | P78527 | 2/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.44 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268135 | 0.93 | ERN1 (0.50) | CGASALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL1589608 | 0.84 | ALDH1A1 (0.65) | ALDH1A1TDP1KDM4ETSHRHPGD | |
| SCHEMBL1002368 | 0.82 | ALDH1A1 (0.69) | ALDH1A1TDP1KDM4ETSHRTRIM24 | |
| SCHEMBL29459687 | 0.82 | ALDH1A1 (0.57) | ALDH1A1TDP1KDM4ETSHRTRIM24 | |
| SCHEMBL1004432 | 0.82 | ALDH1A1 (0.57) | ALDH1A1TDP1KDM4ETSHRTRIM24 | |
| SCHEMBL29459727 | 0.82 | ALDH1A1 (0.69) | ALDH1A1TDP1KDM4ETSHRTRIM24 | |
| SCHEMBL1054210 | 0.81 | ALDH1A1 (0.55) | ALDH1A1TDP1KDM4ETSHRTRIM24 | |
| SCHEMBL12082032 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TDP1KDM4ETSHRHPGD | |
| SCHEMBL286553 | 0.79 | ALDH1A1 (0.53) | CGASALDH1A1TDP1KDM4ETSHR | |
| SCHEMBL6234401 | 0.79 | ERN1 (0.53) | ALDH1A1TDP1KDM4ETSHRTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10947206-B2 | cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2021-03-16 | — | — | US | disclosed |
| US-5015661-A | Lipoxygenase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1991-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947206-B2 | cGAS antagonist compounds | CGAS, STING1, GLS2 | CGAS 1/4885ALDH1A1 3908/4885TDP1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.