SCHEMBL9864709

SCHEMBL9864709

FN(c1ccccc1)N1CCCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSK P43235 1/20 0.38
ALDH1A1 P00352 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
POLB P06746 1/20 0.37
CYP1A2 P05177 5/20 0.35
CYP3A4 P08684 5/20 0.35
CYP2D6 P10635 5/20 0.35
CYP2C9 P11712 5/20 0.35
CYP2C19 P33261 5/20 0.35
KCNA5 P22460 4/20 0.35
KCNH2 Q12809 4/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
KCNE1 P15382 1/20 0.34
MAPT P10636 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27682606 0.81 LMNA (0.45) ALDH1A1SMN1; SMN2POLBCYP1A2CYP2C9
SCHEMBL27620685 0.81 SIGMAR1 (0.45) MEN1KMT2A
SCHEMBL27544631 0.76 HPGD (0.41) ALDH1A1SMN1; SMN2POLBCYP1A2CYP3A4
SCHEMBL1933552 0.74 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2POLBCYP1A2CYP3A4
SCHEMBL11035980 0.73 ALDH1A1 (0.37) CTSKALDH1A1SMN1; SMN2POLBCYP1A2
SCHEMBL18428973 0.72 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2POLBMEN1KMT2A
SCHEMBL8544469 0.72 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2POLBKDM4EMAPT
SCHEMBL473405 0.71 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2POLBCYP1A2CYP3A4
SCHEMBL4991499 0.71 SMN1; SMN2 (0.41) ALDH1A1SMN1; SMN2POLBCYP1A2CYP3A4
SCHEMBL4142245 0.71 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2POLBKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5077160-A PHOTOCONDUCTIVE IMAGING MEMBERS WITH FLUORINATED SQUARAINE COMPOSITIONS XEROX CORPORATION (US) 1991-12-31 US claimed
US-5077160-A PHOTOCONDUCTIVE IMAGING MEMBERS WITH FLUORINATED SQUARAINE COMPOSITIONS XEROX CORPORATION (US) 1991-12-31 US disclosed