Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864827 | 1.00 | HTT (0.41) | HTTUSP2HPGDLMNANPSR1 | |
| SCHEMBL17133880 | 0.65 | LMNA (0.49) | HTTUSP2HPGDLMNANPSR1 | |
| SCHEMBL15761142 | 0.65 | LMNA (0.49) | HTTUSP2HPGDLMNANPSR1 | |
| SCHEMBL9865567 | 0.64 | DRD2 (0.33) | HTTNPSR1MEN1KMT2A | |
| SCHEMBL6644355 | 0.61 | USP2 (0.78) | HTTUSP2HPGDLMNANPSR1 | |
| SCHEMBL8312278 | 0.58 | HTT (0.73) | HTTUSP2HPGDLMNANPSR1 | |
| SCHEMBL13738168 | 0.58 | LMNA (0.49) | HTTUSP2HPGDLMNANPSR1 | |
| SCHEMBL12813394 | 0.58 | HTT (1.00) | HTTHPGDLMNAHSD17B10L3MBTL1 | |
| SCHEMBL13738165 | 0.58 | LMNA (0.49) | HTTUSP2HPGDLMNANPSR1 | |
| SCHEMBL354990 | 0.58 | LMNA (0.49) | HTTHPGDLMNANPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992090-A | Herbicidally active 5,6-dihydrocyclopentathiophenyl-imidazole derivatives | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0347378-A1 | Imidazole derivatives | CIBA-GEIGY AG (CH) | 1989-12-20 | — | — | EP | disclosed |