Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865570 | 1.00 | DRD2 (0.33) | DRD2DRD4HTTNPSR1MEN1 | |
| SCHEMBL6803699 | 0.67 | DRD4 (0.36) | DRD2DRD4 | |
| SCHEMBL9866882 | 0.67 | DRD4 (0.39) | DRD2DRD4NPSR1 | |
| SCHEMBL9864820 | 0.64 | HTT (0.41) | HTTNPSR1MEN1KMT2A | |
| SCHEMBL9579238 | 0.59 | MAOA (0.38) | NPSR1MEN1KMT2A | |
| SCHEMBL9866221 | 0.58 | KDM4E (0.33) | — | |
| SCHEMBL9866219 | 0.58 | KDM4E (0.33) | — | |
| SCHEMBL17133880 | 0.56 | LMNA (0.49) | HTTNPSR1MEN1KMT2A | |
| SCHEMBL1393276 | 0.56 | USP2 (0.38) | NPSR1MEN1KMT2A | |
| SCHEMBL11783227 | 0.53 | ALDH1A1 (0.38) | HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347378-A1 | Imidazole derivatives | CIBA-GEIGY AG (CH) | 1989-12-20 | — | — | EP | claimed |
| US-4992090-A | Herbicidally active 5,6-dihydrocyclopentathiophenyl-imidazole derivatives | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0347378-A1 | Imidazole derivatives | CIBA-GEIGY AG (CH) | 1989-12-20 | — | — | EP | disclosed |