Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.42 |
| ▸ | BCL6 | P41182 | 1/20 | 0.42 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464098 | 0.95 | LMNA (0.49) | LMNAMAPTALDH1A1ABCB1ABCC1 | |
| SCHEMBL9864648 | 0.90 | MAPT (0.53) | LMNAMAPTALDH1A1ABCB1ABCC1 | |
| SCHEMBL10461578 | 0.84 | MAPT (0.53) | LMNAMAPTALDH1A1ABCB1ABCC1 | |
| SCHEMBL6938256 | 0.78 | MEN1 (0.55) | LMNAMAPTALDH1A1SMN1; SMN2HCAR3 | |
| SCHEMBL10889544 | 0.77 | BCL6 (0.52) | LMNAMAPTALDH1A1BCL6BCOR | |
| SCHEMBL10905315 | 0.77 | MAPT (0.47) | LMNAMAPTALDH1A1BCL6BCOR | |
| SCHEMBL13811009 | 0.75 | NPSR1 (0.49) | LMNAMAPTALDH1A1ABCB1ABCC1 | |
| SCHEMBL9864739 | 0.75 | LMNA (0.57) | LMNAMAPTALDH1A1SMN1; SMN2HCAR3 | |
| SCHEMBL10859854 | 0.75 | MAPT (0.56) | LMNAMAPTALDH1A1HCAR3PKM | |
| SCHEMBL4655115 | 0.75 | ALDH1A1 (0.56) | LMNAMAPTALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015769-A | Hair dyes formed by reaction of an alcohol with a phenol in the presence of a strong base for etherification followed by amination | L'OREAL (FR) | 1991-05-14 | — | — | US | disclosed |
| US-4740622-A | 3-amino-4-nitrophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate 4,5-dinitrophenols | L'OREAL (FR) | 1988-04-26 | — | — | US | disclosed |