Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866271 | 0.80 | ALDH1A1 (0.43) | LMNAMAPTALDH1A1KMT2ARAB9A | |
| SCHEMBL6683177 | 0.79 | ALDH1A1 (0.48) | LMNAMAPTALDH1A1KMT2ARAB9A | |
| SCHEMBL6661001 | 0.79 | ALDH1A1 (0.48) | LMNAMAPTALDH1A1KMT2ARAB9A | |
| SCHEMBL9864962 | 0.77 | TSHR (0.44) | LMNAMAPTALDH1A1HCAR3KMT2A | |
| SCHEMBL9865038 | 0.75 | NPC1 (0.45) | LMNAMAPTALDH1A1KMT2ARAB9A | |
| SCHEMBL9865002 | 0.75 | LMNA (0.49) | LMNAMAPTALDH1A1HCAR3KMT2A | |
| SCHEMBL13882647 | 0.75 | ALDH1A1 (0.48) | LMNAMAPTALDH1A1KMT2ARAB9A | |
| SCHEMBL16479673 | 0.74 | KMT2A (0.57) | LMNAMAPTALDH1A1HCAR3KMT2A | |
| SCHEMBL2698755 | 0.74 | LMNA (0.66) | LMNAMAPTALDH1A1HCAR3KMT2A | |
| SCHEMBL5523378 | 0.74 | LMNA (0.66) | LMNAMAPTALDH1A1HCAR3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015769-A | Hair dyes formed by reaction of an alcohol with a phenol in the presence of a strong base for etherification followed by amination | L'OREAL (FR) | 1991-05-14 | — | — | US | disclosed |
| US-4740622-A | 3-amino-4-nitrophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate 4,5-dinitrophenols | L'OREAL (FR) | 1988-04-26 | — | — | US | disclosed |