Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15605993 | 0.80 | GRM5 (0.36) | CES1L3MBTL1RAB9ASMN1; SMN2 | |
| SCHEMBL7516513 | 0.73 | ALDH1A1 (0.44) | CES1 | |
| SCHEMBL10511813 | 0.71 | HPGD (0.40) | CES1L3MBTL1RAB9APTPRC | |
| SCHEMBL6434186 | 0.71 | HTT (0.46) | CES1SMN1; SMN2 | |
| SCHEMBL13363477 | 0.68 | CYP2C19 (0.39) | RAB9A | |
| SCHEMBL30973421 | 0.64 | NOS3 (0.33) | CES1 | |
| SCHEMBL6551637 | 0.64 | NOS2 (0.35) | CES1 | |
| SCHEMBL1745254 | 0.64 | NPSR1 (0.50) | CES1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9984694 | 0.63 | DAO (0.41) | L3MBTL1 | |
| SCHEMBL13575458 | 0.63 | L3MBTL1 (0.32) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992090-A | Herbicidally active 5,6-dihydrocyclopentathiophenyl-imidazole derivatives | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0347378-A1 | Imidazole derivatives | CIBA-GEIGY AG (CH) | 1989-12-20 | — | — | EP | disclosed |