Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 10/20 | 0.37 |
| ▸ | NOS3 | P29474 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865307 | 0.73 | USP2 (0.44) | KMT2ANOS2NOS3USP2 | |
| SCHEMBL9865315 | 0.73 | USP2 (0.44) | KMT2ANOS2NOS3USP2 | |
| SCHEMBL817973 | 0.72 | ACHE (0.46) | KMT2ANOS2NOS3 | |
| SCHEMBL9866519 | 0.69 | NOTUM (0.31) | — | |
| SCHEMBL354098 | 0.67 | ACHE (0.53) | KMT2ANOS2NOS3ALDH1A1DRD2 | |
| SCHEMBL354099 | 0.67 | ACHE (0.53) | KMT2ANOS2NOS3ALDH1A1DRD2 | |
| SCHEMBL5970427 | 0.67 | ACHE (0.53) | KMT2ANOS2NOS3ALDH1A1DRD2 | |
| SCHEMBL14127907 | 0.67 | NOS2 (0.35) | KMT2ANOS2NOS3 | |
| SCHEMBL14024432 | 0.66 | — | — | |
| SCHEMBL8350640 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347378-A1 | Imidazole derivatives | CIBA-GEIGY AG (CH) | 1989-12-20 | — | — | EP | claimed |
| US-4992090-A | Herbicidally active 5,6-dihydrocyclopentathiophenyl-imidazole derivatives | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0347378-A1 | Imidazole derivatives | CIBA-GEIGY AG (CH) | 1989-12-20 | — | — | EP | disclosed |