Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2243227 | 0.94 | NPC1 (0.48) | TP53ACHEBCHENPC1RAB9A | |
| SCHEMBL29626697 | 0.90 | ACHE (0.45) | ACHEBCHENPC1RAB9AHTT | |
| SCHEMBL9701184 | 0.85 | NPC1 (0.51) | ACHENPC1RAB9AHTTKMT2A | |
| SCHEMBL12354613 | 0.80 | NPC1 (0.44) | TP53NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL12354600 | 0.77 | NPC1 (0.42) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL28858711 | 0.74 | LMNA (0.39) | NPC1RAB9AKMT2AMEN1HCRTR2 | |
| SCHEMBL29009654 | 0.72 | TP53 (0.49) | TP53ACHEBCHENPC1RAB9A | |
| SCHEMBL14174100 | 0.70 | NPC1 (0.63) | TP53NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL28211195 | 0.68 | KDM4E (0.43) | TP53NPC1RAB9AHTTKMT2A | |
| SCHEMBL13503759 | 0.68 | NPC1 (0.57) | TP53NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047536-A | Hexahydrobenzo(A)phenanthridine compounds | PURDUE RESEARCH FOUNDATION (US) | 1991-09-10 | — | — | US | disclosed |