Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | CLK1 | P49759 | 2/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865184 | 0.87 | USP7 (0.39) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL9865076 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL27692898 | 0.79 | CYP1A2 (0.42) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL9865502 | 0.71 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL9866096 | 0.70 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| Benzophenone SCHEMBL17818513 | 0.67 | ALDH1A1 (0.64) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| Benzophenone SCHEMBL28319285 | 0.66 | ALDH1A1 (0.70) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL8739630 | 0.65 | ALDH1A1 (0.59) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL257364 | 0.63 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL7489636 | 0.63 | ABCC9 (0.52) | ALDH1A1HPGDKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994485-A | Seed and soil fungi, bacteria | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-02-19 | — | — | US | disclosed |
| EP-0234622-B1 | NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234622-A1 | New thio compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-09-02 | — | — | EP | disclosed |