Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.36 |
| ▸ | CLK1 | P49759 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 4/20 | 0.35 |
| ▸ | CES1 | P23141 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865076 | 0.88 | ALDH1A1 (0.42) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL9864134 | 0.83 | USP7 (0.37) | ALDH1A1HPGDDYRK1ADYRK1BCLK1 | |
| SCHEMBL9865622 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL9864903 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL9876796 | 0.73 | — | — | |
| SCHEMBL10570230 | 0.71 | NPC1 (0.48) | ALDH1A1MAPTKMT2AMEN1DYRK1A | |
| SCHEMBL9865184 | 0.70 | USP7 (0.39) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL9865338 | 0.67 | MEN1 (0.41) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL10566637 | 0.65 | CLK2 (0.44) | ALDH1A1MAPTDYRK1ADYRK1BCES2 | |
| SCHEMBL10570549 | 0.65 | CDK5 (0.58) | ALDH1A1MAPTKMT2AMEN1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994485-A | Seed and soil fungi, bacteria | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-02-19 | — | — | US | disclosed |
| EP-0234622-B1 | NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-06-27 | — | — | EP | disclosed |
| EP-0234622-A1 | New thio compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1987-09-02 | — | — | EP | disclosed |