Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.48 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864590 | 0.95 | PAX8 (0.52) | KDM1AMAOAKDM1BRCOR1PAX8 | |
| SCHEMBL9335800 | 0.88 | KMT2A (0.46) | KDM1AMAOAKDM1BRCOR1PAX8 | |
| SCHEMBL9867345 | 0.85 | NAMPT (0.52) | KDM1AMAOAKDM1BRCOR1PAX8 | |
| SCHEMBL9335609 | 0.84 | SIRT2 (0.49) | KDM1AMAOAKDM1BRCOR1 | |
| SCHEMBL9865766 | 0.84 | SIRT2 (0.49) | KDM1AMAOAKDM1BRCOR1 | |
| SCHEMBL9865584 | 0.83 | NAMPT (0.60) | KDM1AMAOAKDM1BRCOR1PAX8 | |
| SCHEMBL9339505 | 0.83 | PPARG (0.47) | NR1H4 | |
| SCHEMBL9335708 | 0.83 | NR1H4 (0.49) | KDM1AMAOAKDM1BRCOR1PAX8 | |
| SCHEMBL9866050 | 0.83 | GAA (0.54) | KDM1AMAOAKDM1BRCOR1LMNA | |
| SCHEMBL7906639 | 0.82 | MGLL (0.42) | KDM1AMAOAKDM1BRCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |