Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.47 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865134 | 0.95 | HTT (0.53) | GAAKMT2AMEN1L3MBTL1SENP1 | |
| SCHEMBL9335791 | 0.94 | HTT (0.49) | GAAKMT2AMEN1L3MBTL1SENP1 | |
| SCHEMBL9867129 | 0.93 | HDAC6 (0.49) | GAAKMT2AMEN1L3MBTL1SENP1 | |
| SCHEMBL10444691 | 0.93 | HDAC6 (0.49) | GAAKMT2AMEN1L3MBTL1SENP1 | |
| SCHEMBL9867345 | 0.88 | NAMPT (0.52) | SENP1ALDH1A1HPGDHTTKDM1A | |
| SCHEMBL9865584 | 0.86 | NAMPT (0.60) | ALDH1A1HPGDHTTKDM1AMAOA | |
| SCHEMBL9339394 | 0.84 | CA1 (0.51) | GAAL3MBTL1SENP1MAPTPOLB | |
| SCHEMBL7906614 | 0.84 | SENP1 (0.46) | GAAKMT2AMEN1SENP1MAPT | |
| SCHEMBL9335874 | 0.83 | PRMT5 (0.51) | GAAKMT2AMEN1RAB9AMGLL | |
| SCHEMBL27373249 | 0.83 | MGLL (0.60) | RAB9AMGLLHTTKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |