Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927957 | 0.81 | CA12 (0.42) | KDM4EL3MBTL1SMN1; SMN2CYP2D6CYP1A2 | |
| SCHEMBL27995093 | 0.81 | KDM4E (0.47) | KDM4EL3MBTL1LMNAAOC3BCAT2 | |
| SCHEMBL4964891 | 0.78 | CYP2D6 (0.37) | KDM4EL3MBTL1LMNASMN1; SMN2CYP2D6 | |
| SCHEMBL4426990 | 0.76 | LMNA (0.56) | KDM4EL3MBTL1LMNAAOC3BCAT2 | |
| SCHEMBL25941873 | 0.76 | SCN4A (0.55) | — | |
| SCHEMBL424240 | 0.76 | TAAR1 (0.47) | AOC3RIPK1 | |
| SCHEMBL6394437 | 0.76 | TSHR (0.39) | KDM4EL3MBTL1LMNASMN1; SMN2CYP2D6 | |
| SCHEMBL5601501 | 0.74 | ALDH1A1 (0.49) | KDM4EL3MBTL1LMNASMN1; SMN2RAB9A | |
| SCHEMBL15483701 | 0.74 | LMNA (0.54) | KDM4EL3MBTL1LMNAAOC3BCAT2 | |
| SCHEMBL634044 | 0.73 | KDM4E (0.52) | KDM4EL3MBTL1LMNAAOC3BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3991042-A | Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-09 | — | — | US | claimed |
| US-3948877-A | POLYACRYLONITRILE, ACID MODIFIED POLYESTERS OR POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-06 | — | — | US | claimed |
| US-10786530-B2 | Antimicrobial cationic polycarbonates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2020-09-29 | — | — | US | disclosed |
| US-10183099-B2 | Antimicrobial and antifouling catechol-containing polycarbonates for medical applications | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2019-01-22 | — | — | US | disclosed |
| US-9999633-B2 | Antimicrobial cationic polycarbonates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-06-19 | — | — | US | disclosed |
| US-9987369-B2 | Vitamin functionalized gel-forming block copolymers for biomedical applications | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2018-06-05 | — | — | US | disclosed |
| US-9637592-B2 | Vitamin functionalized gel-forming block copolymers for biomedical applications | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-05-02 | — | — | US | disclosed |
| US-9631050-B2 | Antimicrobial cationic polycarbonates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2017-04-25 | — | — | US | disclosed |
| US-5011938-A | Antimicrobials | ELI LILLY AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4940718-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| US-4902707-A | Bicyclic pyrazolidinones, compositions and use | ELI LILLY AND COMPANY (US) | 1990-02-20 | — | — | US | disclosed |
| US-4826992-A | MICROBIOCIDE INTERMEDIATES | ELI LILLY AND COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0310214-A2 | 7-Substituted bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1989-04-05 | — | — | EP | disclosed |
| US-4795815-A | BACTERICIDES, MICROBIOCIDES | ELI LILLY AND COMPANY (US) | 1989-01-03 | — | — | US | disclosed |
| US-4716232-A | 1-(vinyl phosphonate adduct) pyrazolidinones | ELI LILLY AND COMPANY (US) | 1987-12-29 | — | — | US | disclosed |
| EP-0203723-A1 | 2,3-(dihydro)bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-12-03 | — | — | EP | disclosed |
| EP-0203722-A1 | Bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-12-03 | — | — | EP | disclosed |
| EP-0202794-A1 | 7-Substituted-2,3-(Dihydro) bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-26 | — | — | EP | disclosed |
| EP-0202046-A1 | 7-Substituted bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10786530-B2 | Antimicrobial cationic polycarbonates | VDR, GC, CYP24A1 | KDM4E 2314/4885L3MBTL1 1684/4885LMNA 2404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.