Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | CTSV | O60911 | 4/20 | 0.51 |
| ▸ | CTSL | P07711 | 4/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20400859 | 0.91 | NPC1 (0.51) | FOLH1CTSVCTSLMEN1KMT2A | |
| SCHEMBL9865773 | 0.90 | MEN1 (0.47) | CTSVCTSLLRRK2MEN1KMT2A | |
| SCHEMBL10152859 | 0.86 | ALDH1A1 (0.57) | CTSVCTSLMEN1KMT2AKDM4E | |
| SCHEMBL24073948 | 0.85 | TDP1 (0.46) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL9866032 | 0.85 | CA1 (0.50) | FOLH1CTSVCTSLLRRK2NPC1 | |
| SCHEMBL9335648 | 0.83 | LRRK2 (0.46) | LRRK2MEN1KMT2AKDM4ECYP2C9 | |
| SCHEMBL20418351 | 0.83 | RAB9A (0.48) | CTSVCTSLMEN1KMT2AALDH1A1 | |
| SCHEMBL29447700 | 0.83 | RAB9A (0.48) | CTSVCTSLMEN1KMT2AALDH1A1 | |
| SCHEMBL7396740 | 0.82 | MGLL (0.52) | MEN1KMT2AALDH1A1POLBNPC1 | |
| SCHEMBL28526676 | 0.82 | FAAH (0.48) | MEN1KMT2AKDM4EPOLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |