Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865869 | 0.76 | PDE10A (0.57) | CYSLTR1CYSLTR2GFERADAMTS4PDE10A | |
| SCHEMBL9866102 | 0.75 | CYSLTR2 (0.52) | CYSLTR1CYSLTR2ADAMTS4PDE10A | |
| SCHEMBL28620341 | 0.73 | LMNA (0.50) | GAALMNACA1CA2HTT | |
| SCHEMBL9866295 | 0.73 | KDM4E (0.44) | CYSLTR1CYSLTR2GFERADAMTS4KDM4E | |
| SCHEMBL9876648 | 0.73 | CYSLTR2 (0.60) | CYSLTR1CYSLTR2GFERADAMTS4PDE10A | |
| SCHEMBL3362235 | 0.73 | CYSLTR1 (0.63) | CYSLTR1CYSLTR2ADAMTS4GPBAR1 | |
| SCHEMBL5186659 | 0.71 | LMNA (0.58) | KDM4EGAALMNACA1CA2 | |
| SCHEMBL9865792 | 0.71 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2KDM4EMAPTLMNA | |
| SCHEMBL9654592 | 0.71 | ALOX5 (0.60) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL30041498 | 0.71 | KDM4E (0.50) | CYSLTR1CYSLTR2GFERADAMTS4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045547-A | Leukotriene-inhibiting substituted (quinolin-2-yl-methoxy)phenyl-N,N'-sulphonylureas and use thereas | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |