Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10641661 | 0.80 | ADORA3 (0.42) | CA2ELANE | |
| SCHEMBL9868225 | 0.80 | ADORA3 (0.42) | CA2ELANE | |
| SCHEMBL9867503 | 0.79 | ADORA3 (0.52) | CA2 | |
| SCHEMBL9867816 | 0.77 | HSD17B1 (0.46) | CA2 | |
| SCHEMBL9866517 | 0.76 | CA2 (0.51) | CA2 | |
| SCHEMBL9866053 | 0.74 | CA2 (0.43) | CA2 | |
| SCHEMBL9868652 | 0.74 | SOS1 (0.50) | CA2 | |
| SCHEMBL9867241 | 0.73 | CYP2C9 (0.38) | CA2 | |
| SCHEMBL9868097 | 0.73 | CYP19A1 (0.58) | CA2 | |
| SCHEMBL31531294 | 0.73 | ELANE (0.74) | CA2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985450-A | TREATMENT OF GLAUCOMA | AVENTIS PHARMACEUTICALS INC. | 1991-01-15 | — | — | US | claimed |
| US-4985450-A | TREATMENT OF GLAUCOMA | AVENTIS PHARMACEUTICALS INC. | 1991-01-15 | — | — | US | disclosed |
| US-4873239-A | GLAUCOMA TREATMENT | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-10-10 | — | — | US | disclosed |
| EP-0276822-A1 | Arylthiadiazolylsulfonamides and derivatives, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-08-03 | — | — | EP | disclosed |
| US-4758578-A | Arylthiadiazolylsulfonamides, pharmaceutical compositions and use | HOECHST ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-07-19 | — | — | US | disclosed |