Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10374251 | 0.86 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9866046 | 0.76 | ALDH1A1 (0.39) | SMN1; SMN2CA12CA2CA9ALDH1A1 | |
| SCHEMBL9866944 | 0.75 | FEN1 (0.35) | NR3C1 | |
| SCHEMBL9866908 | 0.75 | ALDH1A1 (0.39) | SMN1; SMN2CA12CA2CA9ALDH1A1 | |
| SCHEMBL9866318 | 0.73 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1HTTL3MBTL1 | |
| SCHEMBL9868357 | 0.73 | ALDH1A1 (0.33) | SMN1; SMN2CA12CA2CA9ALDH1A1 | |
| SCHEMBL9866105 | 0.73 | CA12 (0.33) | SMN1; SMN2CA12CA2ALDH1A1KDM4E | |
| SCHEMBL10746083 | 0.71 | LMNA (0.37) | SMN1; SMN2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9865417 | 0.69 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1HTTKDM4E | |
| SCHEMBL9867665 | 0.69 | KEAP1 (0.43) | CA12CA2CA9ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |