Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10374251 | 0.89 | ALDH1A1 (0.39) | ALDH1A1HPGDSMN1; SMN2NR3C1KDM4E | |
| SCHEMBL9868357 | 0.89 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2NR3C1KDM4EPOLB | |
| SCHEMBL9866105 | 0.80 | CA12 (0.33) | ALDH1A1SMN1; SMN2KDM4ENPSR1LMNA | |
| SCHEMBL9866578 | 0.80 | TRPV3 (0.44) | ALDH1A1HPGDSMN1; SMN2NR3C1POLB | |
| SCHEMBL9867387 | 0.78 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2KDM4ENPSR1LMNA | |
| SCHEMBL9866173 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HPGDSMN1; SMN2NPSR1LMNA | |
| SCHEMBL9866464 | 0.76 | NFE2L2 (0.33) | ALDH1A1SMN1; SMN2NR3C1KDM4ELMNA | |
| SCHEMBL9865860 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2NR3C1KDM4EHTT | |
| SCHEMBL9867278 | 0.76 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2KDM4EPOLBLMNA | |
| SCHEMBL9866930 | 0.75 | ALDH1A1 (0.34) | ALDH1A1HPGDNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |