Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865970 | 0.83 | KDM4C (0.50) | HDAC2HDAC8HDAC6HDAC1HDAC3 | |
| SCHEMBL9866777 | 0.81 | ALDH1A1 (0.47) | NPC1RAB9AHDAC2HDAC8HDAC6 | |
| SCHEMBL9866032 | 0.79 | CA1 (0.50) | LTA4HNPC1RAB9AFOLH1HDAC2 | |
| SCHEMBL9866706 | 0.78 | SMN1; SMN2 (0.53) | NPC1RAB9AHDAC2HDAC8HDAC6 | |
| SCHEMBL9335792 | 0.76 | LTA4H (0.46) | LTA4HNPC1RAB9AHDAC2HDAC8 | |
| SCHEMBL9865227 | 0.74 | FOLH1 (0.51) | FOLH1KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL9865221 | 0.74 | FOLH1 (0.53) | NPC1RAB9AFOLH1KDM4EALDH1A1 | |
| SCHEMBL9866212 | 0.72 | KMT2A (0.39) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL9866202 | 0.71 | SMN1; SMN2 (0.55) | NPC1RAB9AHDAC2HDAC8HDAC6 | |
| SCHEMBL9865073 | 0.71 | SMN1; SMN2 (0.54) | NPC1RAB9AHDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |