Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CTSV | O60911 | 3/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865782 | 0.90 | ALDH1A1 (0.42) | FOLH1KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL9865900 | 0.80 | RXRA (0.47) | PTGER1HPGD | |
| SCHEMBL21775803 | 0.79 | FOLH1 (0.62) | FOLH1KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL9867303 | 0.76 | CSNK2A1 (0.42) | KDM4EALDH1A1POLBHPGDMEN1 | |
| SCHEMBL12485977 | 0.75 | CCNB2 (0.44) | L3MBTL1PTGER1SGMS2 | |
| SCHEMBL9866039 | 0.74 | LTA4H (0.46) | FOLH1KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL1648045 | 0.72 | ALDH1A1 (0.73) | FOLH1KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL9865221 | 0.72 | FOLH1 (0.53) | FOLH1KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL1647381 | 0.72 | FOLH1 (0.67) | FOLH1KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL344398 | 0.72 | FOLH1 (0.70) | FOLH1KDM4EALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |