Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866219 | 1.00 | KDM4E (0.33) | KDM4ENPC1TP53PKMRAB9A | |
| SCHEMBL1869054 | 0.61 | MAOA (0.37) | — | |
| SCHEMBL9865567 | 0.58 | DRD2 (0.33) | — | |
| SCHEMBL9579238 | 0.55 | MAOA (0.38) | KDM4ENPC1TP53PKMRAB9A | |
| SCHEMBL11783227 | 0.53 | ALDH1A1 (0.38) | KDM4ESMN1; SMN2 | |
| SCHEMBL2096219 | 0.52 | CYP1A2 (0.38) | KDM4ETP53 | |
| SCHEMBL10142904 | 0.52 | ALDH1A1 (0.38) | KDM4ETP53SMN1; SMN2 | |
| SCHEMBL13609696 | 0.51 | KMT2A (0.54) | — | |
| SCHEMBL467998 | 0.51 | KMT2A (0.54) | — | |
| SCHEMBL9153017 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992090-A | Herbicidally active 5,6-dihydrocyclopentathiophenyl-imidazole derivatives | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0347378-A1 | Imidazole derivatives | CIBA-GEIGY AG (CH) | 1989-12-20 | — | — | EP | disclosed |