Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867620 | 0.87 | ADAMTS4 (0.39) | SMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL9866701 | 0.83 | ALDH1A1 (0.42) | LMNAHTTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9867057 | 0.79 | ALDH1A1 (0.35) | LMNASMN1; SMN2ALDH1A1SLC40A1 | |
| SCHEMBL9867014 | 0.78 | SCN1A (0.31) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9868357 | 0.77 | ALDH1A1 (0.33) | LMNAHTTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL9866105 | 0.76 | CA12 (0.33) | LMNASMN1; SMN2ALDH1A1CA12CA2 | |
| SCHEMBL9868164 | 0.76 | KDM4E (0.40) | HTTALDH1A1POLBGLO1 | |
| SCHEMBL9868123 | 0.76 | ALDH1A1 (0.33) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9867387 | 0.74 | ALDH1A1 (0.35) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9866038 | 0.74 | PDE4A (0.37) | LMNASMN1; SMN2ALDH1A1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |