Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866248 | 0.87 | LMNA (0.45) | SMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL9866701 | 0.85 | ALDH1A1 (0.42) | SMN1; SMN2NFE2L2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL9867057 | 0.83 | ALDH1A1 (0.35) | SMN1; SMN2NFE2L2KDM4ENPSR1ALDH1A1 | |
| SCHEMBL9867014 | 0.82 | SCN1A (0.31) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9866038 | 0.81 | PDE4A (0.37) | ADAMTS4SMN1; SMN2NFE2L2KDM4ENPSR1 | |
| SCHEMBL9868357 | 0.81 | ALDH1A1 (0.33) | SMN1; SMN2NFE2L2KDM4ENPSR1ALDH1A1 | |
| SCHEMBL9866105 | 0.80 | CA12 (0.33) | SMN1; SMN2NFE2L2KDM4ENPSR1ALDH1A1 | |
| SCHEMBL9868164 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL9868123 | 0.80 | ALDH1A1 (0.33) | SMN1; SMN2NFE2L2KDM4ENPSR1ALDH1A1 | |
| SCHEMBL9868013 | 0.79 | PPARG (0.46) | NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |