Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869208 | 0.77 | ALDH1A1 (0.43) | KDM4EALDH1A1LMNASMN1; SMN2GFER | |
| SCHEMBL9867413 | 0.75 | TRPV3 (0.46) | ALDH1A1ADAMTS4MMP13POLBLMNA | |
| SCHEMBL28969166 | 0.73 | ACACB (0.45) | ALDH1A1ACACBLMNA | |
| SCHEMBL28969194 | 0.73 | ACACB (0.45) | ALDH1A1ACACBLMNA | |
| SCHEMBL30313723 | 0.73 | ACACB (0.45) | ALDH1A1ACACBLMNA | |
| SCHEMBL24646024 | 0.73 | ACACB (0.45) | ALDH1A1ACACBLMNA | |
| SCHEMBL30171098 | 0.72 | ACACB (0.46) | ALDH1A1ACACBLMNAGAA | |
| SCHEMBL13154794 | 0.72 | ACACB (0.46) | ALDH1A1ACACBLMNAGAA | |
| SCHEMBL9868000 | 0.70 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2GFERMEN1KMT2A | |
| SCHEMBL25820335 | 0.70 | GFER (0.46) | KDM4EALDH1A1SMN1; SMN2GFERMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |