Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866578 | 0.89 | TRPV3 (0.44) | TRPV3KAT8ADAMTS4GAAALDH1A1 | |
| SCHEMBL9865969 | 0.85 | TRPV3 (0.45) | TRPV3KAT8ADAMTS4GAAALDH1A1 | |
| SCHEMBL9866569 | 0.81 | AR (0.51) | KAT8HPGDPOLBNPC1AR | |
| SCHEMBL9866681 | 0.81 | KAT8 (0.47) | TRPV3KAT8ADAMTS4ALDH1A1LMNA | |
| SCHEMBL9867527 | 0.79 | TRPV3 (0.44) | TRPV3KAT8ADAMTS4GAAALDH1A1 | |
| SCHEMBL9866804 | 0.79 | POLB (0.47) | TRPV3KAT8ALDH1A1HPGDLMNA | |
| SCHEMBL9865486 | 0.78 | KMT2A (0.43) | TRPV3KAT8ALDH1A1HTTAR | |
| SCHEMBL9734839 | 0.77 | CA1 (0.50) | TRPV3KAT8ALDH1A1NUDT1PKM | |
| SCHEMBL9867620 | 0.77 | ADAMTS4 (0.39) | ADAMTS4GAAALDH1A1HPGDTSHR | |
| SCHEMBL9868357 | 0.77 | ALDH1A1 (0.33) | GAAALDH1A1LMNAHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |