Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866285 | 0.79 | PDE10A (0.62) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5 | |
| SCHEMBL9865885 | 0.78 | GPBAR1 (0.57) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5 | |
| SCHEMBL9719811 | 0.77 | GPBAR1 (0.62) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5 | |
| SCHEMBL7008427 | 0.77 | GPBAR1 (0.64) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5 | |
| SCHEMBL9632136 | 0.77 | PDE10A (0.54) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5 | |
| SCHEMBL9447067 | 0.76 | AR (0.64) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5 | |
| SCHEMBL9865828 | 0.75 | CYSLTR1 (0.62) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5 | |
| SCHEMBL9054564 | 0.75 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2ALOX5FFAR1AKR1B1 | |
| SCHEMBL9632132 | 0.74 | ADAMTS4 (0.52) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5 | |
| SCHEMBL10544630 | 0.74 | CYSLTR1 (0.84) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045547-A | Leukotriene-inhibiting substituted (quinolin-2-yl-methoxy)phenyl-N,N'-sulphonylureas and use thereas | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |