Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835199 | 0.77 | NPC1 (0.39) | NPC1SMN1; SMN2RAB9AHPGDNFKB1 | |
| SCHEMBL9835414 | 0.73 | MAPT (0.42) | NPC1SMN1; SMN2RAB9AHPGDALDH1A1 | |
| SCHEMBL1801329 | 0.70 | ALDH1A1 (0.62) | NPC1SMN1; SMN2RAB9AHPGDNFKB1 | |
| SCHEMBL31236186 | 0.70 | ALDH1A1 (0.62) | NPC1SMN1; SMN2RAB9AHPGDNFKB1 | |
| SCHEMBL31236185 | 0.70 | ALDH1A1 (0.62) | NPC1SMN1; SMN2RAB9AHPGDNFKB1 | |
| SCHEMBL7749402 | 0.67 | SMN1; SMN2 (0.50) | NPC1SMN1; SMN2RAB9AHPGDNFKB1 | |
| SCHEMBL7749404 | 0.67 | SMN1; SMN2 (0.50) | NPC1SMN1; SMN2RAB9AHPGDNFKB1 | |
| SCHEMBL27353074 | 0.66 | FPR2 (0.44) | NPC1SMN1; SMN2RAB9AHPGDNFKB1 | |
| SCHEMBL9833989 | 0.65 | RXFP1 (0.41) | NPC1SMN1; SMN2RAB9AHPGDALDH1A1 | |
| SCHEMBL9867843 | 0.65 | MEN1 (0.41) | SMN1; SMN2RAB9AHPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983751-A | Chemical intermediates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-08 | — | — | US | disclosed |