Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HTR3A | P46098 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865616 | 0.82 | HTR1A (0.59) | HRH3HTR1ADRD4HTR2AHTR2C | |
| SCHEMBL9866440 | 0.76 | MCHR1 (0.40) | HRH3HTR1ADRD4HTR2AHTR2C | |
| SCHEMBL9866278 | 0.75 | HRH3 (0.47) | HRH3MEN1KMT2ACACNA1B | |
| SCHEMBL9602082 | 0.72 | HRH3 (0.45) | HRH3KMT2ADRD2CACNA1B | |
| SCHEMBL9866508 | 0.72 | HTR1A (0.43) | HRH3HTR1ADRD4HTR2AHTR2C | |
| SCHEMBL1374617 | 0.69 | HRH3 (1.00) | HRH3HTR3A | |
| SCHEMBL1374619 | 0.69 | HRH3 (1.00) | HRH3HTR3A | |
| SCHEMBL14287611 | 0.68 | MAOB (0.69) | HRH3 | |
| SCHEMBL14310794 | 0.67 | HRH3 (0.72) | HRH3HTR3A | |
| SCHEMBL27236993 | 0.65 | DRD3 (1.00) | HRH3HTR1ADRD4HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |