Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 5/20 | 1.00 |
| ▸ | HTR1A | P08908 | 4/20 | 1.00 |
| ▸ | HTR2A | P28223 | 4/20 | 1.00 |
| ▸ | HTR7 | P34969 | 4/20 | 1.00 |
| ▸ | HTR2C | P28335 | 3/20 | 1.00 |
| ▸ | DRD4 | P21917 | 2/20 | 1.00 |
| ▸ | DRD2 | P14416 | 4/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.72 |
| ▸ | MAOB | P27338 | 5/20 | 0.68 |
| ▸ | MAOA | P21397 | 4/20 | 0.68 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.67 |
| ▸ | DRD1 | P21728 | 2/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | DRD5 | P21918 | 1/20 | 0.61 |
| ▸ | HRH1 | P35367 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27236995 | 0.84 | DRD2 (1.00) | DRD3HTR1AHTR2AHTR7HTR2C | |
| SCHEMBL11282783 | 0.83 | DRD3 (0.70) | DRD3HTR1AHTR2AHTR7HTR2C | |
| SCHEMBL29786320 | 0.82 | DRD2 (0.81) | DRD3HTR1AHTR2AHTR7HTR2C | |
| SCHEMBL20512965 | 0.82 | DRD2 (0.81) | DRD3HTR1AHTR2AHTR7HTR2C | |
| SCHEMBL6329923 | 0.81 | HRH3 (1.00) | DRD3HTR1AHTR2AHTR7HTR2C | |
| SCHEMBL11267442 | 0.80 | MAOB (0.67) | DRD3HTR1AHTR2AHTR7HTR2C | |
| SCHEMBL23409205 | 0.77 | DRD3 (0.62) | DRD3HTR1AHTR2AHTR7HTR2C | |
| SCHEMBL9825963 | 0.76 | SLC6A4 (0.73) | DRD3HTR1AHTR2AHTR7HTR2C | |
| Hydrochloric Acid SCHEMBL9826980 | 0.75 | SLC6A4 (0.71) | DRD3HTR1AHTR2AHTR7HTR2C | |
| SCHEMBL8687394 | 0.75 | DRD3 (0.65) | DRD3HTR1AHTR2AHTR7HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12006301-B1 | And synthesis of dual 5-HT1A and 5-HT7 receptor ligands | FLORIDA A&M UNIVERSITY (US) | 2024-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12006301-B1 | And synthesis of dual 5-HT1A and 5-HT7 receptor ligands | HTR7, HTR1A, HTR5A | DRD3 119/4885HTR1A 2/4885HTR2A 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.